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Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
Engineering microbes to produce plant-derived natural products provides an alternate solution to obtain bioactive products. Here we report a systematic approach to sequentially identify the rate-limiting steps and improve the biosynthesis of the cannabinoid precursor olivetolic acid (OLA) in Yarrowi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653464/ https://www.ncbi.nlm.nih.gov/pubmed/36371560 http://dx.doi.org/10.1038/s42003-022-04202-1 |