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Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine

The importance of modified peptides and proteins for applications in drug discovery, and for illuminating biological processes at the molecular level, is fueling a demand for efficient methods that facilitate the precise modification of these biomolecules. Herein, we describe the development of a ph...

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Detalles Bibliográficos
Autores principales: Dowman, Luke J., Kulkarni, Sameer S., Alegre-Requena, Juan V., Giltrap, Andrew M., Norman, Alexander R., Sharma, Ashish, Gallegos, Liliana C., Mackay, Angus S., Welegedara, Adarshi P., Watson, Emma E., van Raad, Damian, Niederacher, Gerhard, Huhmann, Susanne, Proschogo, Nicholas, Patel, Karishma, Larance, Mark, Becker, Christian F. W., Mackay, Joel P., Lakhwani, Girish, Huber, Thomas, Paton, Robert S., Payne, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653470/
https://www.ncbi.nlm.nih.gov/pubmed/36371402
http://dx.doi.org/10.1038/s41467-022-34530-z