Obesity downregulates lipid metabolism genes in first trimester placenta

Placentas of obese women have low mitochondrial β-oxidation of fatty acids (FA) and accumulate lipids in late pregnancy. This creates a lipotoxic environment, impairing placental efficiency. We hypothesized that placental FA metabolism is impaired in women with obesity from early pregnancy. We asses...

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Detalles Bibliográficos
Autores principales: Rasool, Aisha, Mahmoud, Taysir, Mathyk, Begum, Kaneko-Tarui, Tomoko, Roncari, Danielle, White, Katharine O., O’Tierney-Ginn, Perrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653480/
https://www.ncbi.nlm.nih.gov/pubmed/36371454
http://dx.doi.org/10.1038/s41598-022-24040-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653480/
https://www.ncbi.nlm.nih.gov/pubmed/36371454
http://dx.doi.org/10.1038/s41598-022-24040-9

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