ADCK1 is a potential therapeutic target of osteosarcoma

We here showed that ADCK1 (AarF domain-containing kinase 1), a mitochondrial protein, is upregulated in human osteosarcoma (OS) tissues and OS cells. In primary and established OS cells, ADCK1 shRNA or CRISPR/Cas9-induced ADCK1 knockout (KO) remarkably inhibited cell viability, proliferation and mig...

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Detalles Bibliográficos
Autores principales: Zhuo, Bao-biao, Zhu, Lun-qing, Yao, Chen, Wang, Xi-hua, Li, Shi-xian, Wang, Rong, Li, Yuan, Ling, Zhuo-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653483/
https://www.ncbi.nlm.nih.gov/pubmed/36371387
http://dx.doi.org/10.1038/s41419-022-05401-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653483/
https://www.ncbi.nlm.nih.gov/pubmed/36371387
http://dx.doi.org/10.1038/s41419-022-05401-8

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