Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD

BACKGROUND AND AIMS: Bile acids are hepatic metabolites and have many properties considered to be relevant to the pathophysiology of NAFLD. Circulating levels of the intestinal microbiome‐modified bile acid deoxycholate are increased in cirrhosis. APPROACH AND RESULTS: To further elucidate the role...

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Detalles Bibliográficos
Autores principales: Smirnova, Ekaterina, Muthiah, Mark D., Narayan, Nicole, Siddiqui, Mohamad S., Puri, Puneet, Luketic, Velimir A., Contos, Melissa J., Idowu, Michael, Chuang, Jen‐Chieh, Billin, Andrew N., Huss, Ryan S., Myers, Robert P., Boyett, Sherry, Seneshaw, Mulugeta, Min, Hae‐Ki, Mirshahi, Faridodin, Sanyal, Arun J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653520/
https://www.ncbi.nlm.nih.gov/pubmed/35561146
http://dx.doi.org/10.1002/hep.32568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653520/
https://www.ncbi.nlm.nih.gov/pubmed/35561146
http://dx.doi.org/10.1002/hep.32568

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