Cargando…
Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD
BACKGROUND AND AIMS: Bile acids are hepatic metabolites and have many properties considered to be relevant to the pathophysiology of NAFLD. Circulating levels of the intestinal microbiome‐modified bile acid deoxycholate are increased in cirrhosis. APPROACH AND RESULTS: To further elucidate the role...
Autores principales: | Smirnova, Ekaterina, Muthiah, Mark D., Narayan, Nicole, Siddiqui, Mohamad S., Puri, Puneet, Luketic, Velimir A., Contos, Melissa J., Idowu, Michael, Chuang, Jen‐Chieh, Billin, Andrew N., Huss, Ryan S., Myers, Robert P., Boyett, Sherry, Seneshaw, Mulugeta, Min, Hae‐Ki, Mirshahi, Faridodin, Sanyal, Arun J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653520/ https://www.ncbi.nlm.nih.gov/pubmed/35561146 http://dx.doi.org/10.1002/hep.32568 |
Ejemplares similares
-
Development of Alcohol‐Associated Hepatitis Is Associated With Specific Changes in Gut‐Modified Bile Acids
por: Muthiah, Mark D., et al.
Publicado: (2022) -
Second-Harmonic Generated Quantifiable Fibrosis Parameters Provide Signatures for Disease Progression and Regression in Nonalcoholic Fatty Liver Disease
por: Ng, Nicole, et al.
Publicado: (2023) -
Restoration of CD4(+) T Cells during NAFLD without Modulation of the Hepatic Immunological Pattern Is Not Sufficient to Prevent HCC
por: Isbell, Madison, et al.
Publicado: (2022) -
Increased hepatic and circulating chemokine and osteopontin expression occurs early in human NAFLD development
por: Kriss, Michael, et al.
Publicado: (2020) -
An Evaluation of the Collagen Fragments Related to Fibrogenesis and Fibrolysis in Nonalcoholic Steatohepatitis
por: Luo, Yi, et al.
Publicado: (2018)