Regulation of Cyclooxygenase-2 Expression in Human T Cells by Glucocorticoid Receptor-Mediated Transrepression of Nuclear Factor of Activated T Cells

Cyclooxygenase (COX) is the key enzyme in prostanoid synthesis from arachidonic acid (AA). Two isoforms, named COX-1 and COX-2, are expressed in mammalian tissues. The expression of COX-2 isoform is induced by several stimuli including cytokines and mitogens, and this induction is inhibited by gluco...

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Detalles Bibliográficos
Autores principales: Cacheiro-Llaguno, Cristina, Hernández-Subirá, Elena, Díaz-Muñoz, Manuel D., Fresno, Manuel, Serrador, Juan M., Íñiguez, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653600/
https://www.ncbi.nlm.nih.gov/pubmed/36362060
http://dx.doi.org/10.3390/ijms232113275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653600/
https://www.ncbi.nlm.nih.gov/pubmed/36362060
http://dx.doi.org/10.3390/ijms232113275

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