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GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway

Glial cell line-derived neurotrophic factor (GDNF) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. The mechanisms underlying this effect have not been investigated. We here demonstrate for the first...

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Detalles Bibliográficos
Autores principales: Mikroulis, Apostolos, Waloschková, Eliška, Bengzon, Johan, Woldbye, David, Pinborg, Lars H., Jespersen, Bo, Avila, Anna Sanchez, Laszlo, Zsofia I., Henstridge, Christopher, Ledri, Marco, Kokaia, Merab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653719/
https://www.ncbi.nlm.nih.gov/pubmed/36361981
http://dx.doi.org/10.3390/ijms232113190