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GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway
Glial cell line-derived neurotrophic factor (GDNF) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. The mechanisms underlying this effect have not been investigated. We here demonstrate for the first...
Autores principales: | Mikroulis, Apostolos, Waloschková, Eliška, Bengzon, Johan, Woldbye, David, Pinborg, Lars H., Jespersen, Bo, Avila, Anna Sanchez, Laszlo, Zsofia I., Henstridge, Christopher, Ledri, Marco, Kokaia, Merab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653719/ https://www.ncbi.nlm.nih.gov/pubmed/36361981 http://dx.doi.org/10.3390/ijms232113190 |
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