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Molecular Docking and Molecular Dynamics Studies Reveal Secretory Proteins as Novel Targets of Temozolomide in Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is a tumor of glial origin and is the most malignant, aggressive and prevalent type, with the highest mortality rate in adult brain cancer. Surgical resection of the tumor followed by Temozolomide (TMZ) therapy is currently available, but the development of resistance t...

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Detalles Bibliográficos
Autores principales: Sumera, Anwer, Farha, Waseem, Maaz, Fatima, Areeba, Malik, Nishat, Ali, Amjad, Zahid, Saadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653723/
https://www.ncbi.nlm.nih.gov/pubmed/36364024
http://dx.doi.org/10.3390/molecules27217198