Cargando…
Molecular Docking and Molecular Dynamics Studies Reveal Secretory Proteins as Novel Targets of Temozolomide in Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is a tumor of glial origin and is the most malignant, aggressive and prevalent type, with the highest mortality rate in adult brain cancer. Surgical resection of the tumor followed by Temozolomide (TMZ) therapy is currently available, but the development of resistance t...
Autores principales: | Sumera, Anwer, Farha, Waseem, Maaz, Fatima, Areeba, Malik, Nishat, Ali, Amjad, Zahid, Saadia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653723/ https://www.ncbi.nlm.nih.gov/pubmed/36364024 http://dx.doi.org/10.3390/molecules27217198 |
Ejemplares similares
-
Temozolomide resistance in glioblastoma multiforme
por: Lee, Sang Y.
Publicado: (2016) -
Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Rosmarinus officinalis against Alzheimer’s Disease
por: Mirza, Fatima Javed, et al.
Publicado: (2022) -
Effectiveness of temozolomide for primary glioblastoma multiforme in routine clinical practice
por: van Genugten, J. A. B., et al.
Publicado: (2009) -
Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems
por: Toren, Amos, et al.
Publicado: (2016) -
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide
por: Wang, Nan, et al.
Publicado: (2021)