Levetiracetam Ameliorates Doxorubicin-Induced Chemobrain by Enhancing Cholinergic Transmission and Reducing Neuroinflammation Using an Experimental Rat Model and Molecular Docking Study

Cancer chemotherapy-induced cognitive impairment (chemobrain) is a major complication that affects the prognosis of therapy. Our study evaluates the nootropic-like activity of levetiracetam (LEVE) against doxorubicin (DOX)-induced memory defects using in vivo and molecular modelling. Rats were treat...

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Detalles Bibliográficos
Autores principales: Mani, Vasudevan, Arfeen, Minhajul, Rabbani, Syed Imam, Shariq, Ali, Amirthalingam, Palanisamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653834/
https://www.ncbi.nlm.nih.gov/pubmed/36364190
http://dx.doi.org/10.3390/molecules27217364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653834/
https://www.ncbi.nlm.nih.gov/pubmed/36364190
http://dx.doi.org/10.3390/molecules27217364

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