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Levetiracetam Ameliorates Doxorubicin-Induced Chemobrain by Enhancing Cholinergic Transmission and Reducing Neuroinflammation Using an Experimental Rat Model and Molecular Docking Study

Cancer chemotherapy-induced cognitive impairment (chemobrain) is a major complication that affects the prognosis of therapy. Our study evaluates the nootropic-like activity of levetiracetam (LEVE) against doxorubicin (DOX)-induced memory defects using in vivo and molecular modelling. Rats were treat...

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Detalles Bibliográficos
Autores principales:	Mani, Vasudevan, Arfeen, Minhajul, Rabbani, Syed Imam, Shariq, Ali, Amirthalingam, Palanisamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653834/ https://www.ncbi.nlm.nih.gov/pubmed/36364190 http://dx.doi.org/10.3390/molecules27217364

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