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Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts

Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by natural IgM antibodies and low levels of these antibodies have been associated with human vein graft (VG) failure. Although PC...

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Detalles Bibliográficos
Autores principales: Baganha, Fabiana, Sluiter, Thijs J., de Jong, Rob C. M., van Alst, Louise A., Peters, Hendrika A. B., Jukema, J. Wouter, Delibegovic, Mirela, Pettersson, Knut, Quax, Paul H. A., de Vries, Margreet R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653839/
https://www.ncbi.nlm.nih.gov/pubmed/36362449
http://dx.doi.org/10.3390/ijms232113662