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CD73-Mediated Formation of Extracellular Adenosine Is Responsible for Adenosine A(2A) Receptor-Mediated Control of Fear Memory and Amygdala Plasticity

Adenosine A(2A) receptors (A(2A)R) control fear memory and the underlying processes of synaptic plasticity in the amygdala. In other brain regions, A(2A)R activation is ensured by ATP-derived extracellular adenosine formed by ecto-5′-nucleotidase or CD73. We now tested whether CD73 is also responsib...

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Detalles Bibliográficos
Autores principales: Simões, Ana Patrícia, Gonçalves, Francisco Q., Rial, Daniel, Ferreira, Samira G., Lopes, João Pedro, Canas, Paula M., Cunha, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653840/
https://www.ncbi.nlm.nih.gov/pubmed/36361618
http://dx.doi.org/10.3390/ijms232112826