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Comparative Preclinical Evaluation of Peptide-Based Chelators for the Labeling of DARPin G3 with (99m)Tc for Radionuclide Imaging of HER2 Expression in Cancer

Non-invasive radionuclide imaging of human epidermal growth factor receptor type 2 (HER2) expression in breast, gastroesophageal, and ovarian cancers may stratify patients for treatment using HER2-targeted therapeutics. Designed ankyrin repeat proteins (DARPins) are a promising type of targeting pro...

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Detalles Bibliográficos
Autores principales: Larkina, Mariia, Plotnikov, Evgenii, Bezverkhniaia, Ekaterina, Shabanova, Yulia, Tretyakova, Maria, Yuldasheva, Feruza, Zelchan, Roman, Schulga, Alexey, Konovalova, Elena, Vorobyeva, Anzhelika, Garousi, Javad, Gräslund, Torbjörn, Belousov, Mikhail, Tolmachev, Vladimir, Deyev, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653920/
https://www.ncbi.nlm.nih.gov/pubmed/36362226
http://dx.doi.org/10.3390/ijms232113443