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Simultaneous Degradation Study of Isomers in Human Plasma by HPLC-MS/MS and Application of LEDA Algorithm for Their Characterization

This paper proposes a tandem mass spectrometry (MS/MS) approach in isomer recognition by playing in the “energetic dimension” of the experiment. The chromatographic set up (HPLC) was tuned to minimize the run time, without requiring high efficiency or resolution between the isomers. Then, the MS/MS...

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Detalles Bibliográficos
Autores principales: Pallecchi, Marco, Braconi, Laura, Menicatti, Marta, Giachetti, Sara, Dei, Silvia, Teodori, Elisabetta, Bartolucci, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653966/
https://www.ncbi.nlm.nih.gov/pubmed/36361928
http://dx.doi.org/10.3390/ijms232113139