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Epigenetic Reprogramming of Kaposi’s Sarcoma-Associated Herpesvirus during Hypoxic Reactivation

SIMPLE SUMMARY: Epigenetic reprogramming of the KSHV genome plays a central role in lytic replication of Kaposi’s sarcoma-associated herpesvirus (KSHV). Hypoxia, a common phenotype of cancer cells, exerts a negative effect on DNA replication. Interestingly, KSHV is known to bypass this repression an...

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Detalles Bibliográficos
Autores principales: Singh, Rajnish Kumar, Bose, Dipayan, Robertson, Erle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654037/
https://www.ncbi.nlm.nih.gov/pubmed/36358814
http://dx.doi.org/10.3390/cancers14215396