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Green Solvents for Eco-Friendly Synthesis of Dimethindene: A Forward-Looking Approach

Dimethindene is a selective histamine H(1) antagonist and is commercially available as a racemate. Upon analyzing the synthetic pathways currently available for the industrial preparation of dimethindene, we set up a sustainable approach for the synthesis of this drug, switching from petroleum-based...

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Detalles Bibliográficos
Autores principales: Quivelli, Andrea Francesca, Rossi, Federico Vittorio, Alario, Chiara, Sannicolò, Francesco, Vitale, Paola, García-Álvarez, Joaquín, Perna, Filippo Maria, Capriati, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654048/
https://www.ncbi.nlm.nih.gov/pubmed/36364422
http://dx.doi.org/10.3390/molecules27217594