Cargando…

Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein

The protein lysine deacylases of the NAD(+)-dependent Sirtuin family contribute to metabolic regulation, stress responses, and aging processes, and the human Sirtuin isoforms, Sirt1-7, are considered drug targets for aging-related diseases. The nuclear isoform Sirt1 deacetylates histones and transcr...

Descripción completa

Detalles Bibliográficos
Autores principales: Weiss, Sandra, Adolph, Ramona S., Schweimer, Kristian, DiFonzo, Andrea, Meleshin, Marat, Schutkowski, Mike, Steegborn, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654219/
https://www.ncbi.nlm.nih.gov/pubmed/36361557
http://dx.doi.org/10.3390/ijms232112764