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Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein
The protein lysine deacylases of the NAD(+)-dependent Sirtuin family contribute to metabolic regulation, stress responses, and aging processes, and the human Sirtuin isoforms, Sirt1-7, are considered drug targets for aging-related diseases. The nuclear isoform Sirt1 deacetylates histones and transcr...
Autores principales: | Weiss, Sandra, Adolph, Ramona S., Schweimer, Kristian, DiFonzo, Andrea, Meleshin, Marat, Schutkowski, Mike, Steegborn, Clemens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654219/ https://www.ncbi.nlm.nih.gov/pubmed/36361557 http://dx.doi.org/10.3390/ijms232112764 |
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