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AmyP53, a Therapeutic Peptide Candidate for the Treatment of Alzheimer’s and Parkinson’s Disease: Safety, Stability, Pharmacokinetics Parameters and Nose-to Brain Delivery

Neurodegenerative disorders are a major public health issue. Despite decades of research efforts, we are still seeking an efficient cure for these pathologies. The initial paradigm of large aggregates of amyloid proteins (amyloid plaques, Lewis bodies) as the root cause of Alzheimer’s and Parkinson’...

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Detalles Bibliográficos
Autores principales: Di Scala, Coralie, Armstrong, Nicholas, Chahinian, Henri, Chabrière, Eric, Fantini, Jacques, Yahi, Nouara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654333/
https://www.ncbi.nlm.nih.gov/pubmed/36362170
http://dx.doi.org/10.3390/ijms232113383