Cargando…

Optimized Transcriptional Signature for Evaluation of MEK/ERK Pathway Baseline Activity and Long-Term Modulations in Ovarian Cancer

Ovarian cancer is the most aggressive and lethal of all gynecologic malignancies. The high activity of the MEK/ERK signaling pathway is tightly associated with tumor growth, high recurrence rate, and treatment resistance. Several transcriptional signatures were proposed recently for evaluation of ME...

Descripción completa

Detalles Bibliográficos
Autores principales: Chesnokov, Mikhail S., Yadav, Anil, Chefetz, Ilana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654336/
https://www.ncbi.nlm.nih.gov/pubmed/36362153
http://dx.doi.org/10.3390/ijms232113365