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Optimized Transcriptional Signature for Evaluation of MEK/ERK Pathway Baseline Activity and Long-Term Modulations in Ovarian Cancer

Ovarian cancer is the most aggressive and lethal of all gynecologic malignancies. The high activity of the MEK/ERK signaling pathway is tightly associated with tumor growth, high recurrence rate, and treatment resistance. Several transcriptional signatures were proposed recently for evaluation of ME...

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Detalles Bibliográficos
Autores principales:	Chesnokov, Mikhail S., Yadav, Anil, Chefetz, Ilana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654336/ https://www.ncbi.nlm.nih.gov/pubmed/36362153 http://dx.doi.org/10.3390/ijms232113365

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