Quantification of Cardiotonic Steroids Potentially Regulated by Paraoxonase 3 in a Rat Model of Chronic Kidney Disease Using UHPLC-Orbitrap-MS

Endogenous cardiotonic steroids (CTSs), such as telocinobufagin (TCB) and marinobufagin (MBG) contain a lactone moiety critical to their binding and signaling through the Na(+)/K(+)-ATPase. Their concentrations elevate in response to sodium intake and under volume-expanded conditions. Paraoxonase 3...

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Detalles Bibliográficos
Autores principales: Lamichhane, Sabitri, Mohammed, Chrysan J., Haller, Steven T., Kennedy, David J., Isailovic, Dragan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654389/
https://www.ncbi.nlm.nih.gov/pubmed/36362352
http://dx.doi.org/10.3390/ijms232113565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654389/
https://www.ncbi.nlm.nih.gov/pubmed/36362352
http://dx.doi.org/10.3390/ijms232113565

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