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Conservation and Diversification of tRNA t(6)A-Modifying Enzymes across the Three Domains of Life

The universal N(6)-threonylcarbamoyladenosine (t(6)A) modification occurs at position 37 of tRNAs that decipher codons starting with adenosine. Mechanistically, t(6)A stabilizes structural configurations of the anticodon stem loop, promotes anticodon–codon pairing and safeguards the translational fi...

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Detalles Bibliográficos
Autores principales: Su, Chenchen, Jin, Mengqi, Zhang, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654439/
https://www.ncbi.nlm.nih.gov/pubmed/36362385
http://dx.doi.org/10.3390/ijms232113600