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Conservation and Diversification of tRNA t(6)A-Modifying Enzymes across the Three Domains of Life
The universal N(6)-threonylcarbamoyladenosine (t(6)A) modification occurs at position 37 of tRNAs that decipher codons starting with adenosine. Mechanistically, t(6)A stabilizes structural configurations of the anticodon stem loop, promotes anticodon–codon pairing and safeguards the translational fi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654439/ https://www.ncbi.nlm.nih.gov/pubmed/36362385 http://dx.doi.org/10.3390/ijms232113600 |