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Multiplexed Digital Spatial Protein Profiling Reveals Distinct Phenotypes of Mononuclear Phagocytes in Livers with Advanced Fibrosis

Background and Aims: Intrahepatic mononuclear phagocytes (MPs) are critical for the initiation and progression of liver fibrosis. In this study, using multiplexed digital spatial protein profiling, we aimed to derive a unique protein signature predicting advanced liver fibrosis. Methods: Snap-frozen...

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Detalles Bibliográficos
Autores principales: Lee, Jaejun, Kim, Chang Min, Cha, Jung Hoon, Park, Jin Young, Yu, Yun Suk, Wang, Hee Jung, Sung, Pil Soo, Jung, Eun Sun, Bae, Si Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654480/
https://www.ncbi.nlm.nih.gov/pubmed/36359782
http://dx.doi.org/10.3390/cells11213387