Potent Alkaline Phosphatase Inhibitors, Pyrazolo-Oxothiazolidines: Synthesis, Biological Evaluation, Molecular Docking, and Kinetic Studies

To develop new alkaline phosphatase inhibitors (ALP), a series of pyrazolo-oxothiazolidine derivatives were synthesized and biologically assessed, and the results showed that all of the synthesized compounds significantly inhibited ALP. Specifically, compound 7g displayed the strongest inhibitory ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Hosseini Nasab, Narges, Raza, Hussain, Shim, Rok Su, Hassan, Mubashir, Kloczkowski, Andrzej, Kim, Song Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654533/
https://www.ncbi.nlm.nih.gov/pubmed/36362051
http://dx.doi.org/10.3390/ijms232113262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654533/
https://www.ncbi.nlm.nih.gov/pubmed/36362051
http://dx.doi.org/10.3390/ijms232113262

Ejemplares similares