Deep Molecular and In Silico Protein Analysis of p53 Alteration in Myelodysplastic Neoplasia and Acute Myeloid Leukemia

Background: Mutation of the TP53 gene is one of the major drivers of myelodysplastic neoplasias (MDS) and acute myeloid leukemia with myelodysplasia-related changes (AML-MR). TP53 mutations present in these hematopoietic malignancies form a distinct molecular genetic cluster with a worse prognosis t...

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Detalles Bibliográficos
Autores principales: Madarász, Kristóf, Mótyán, János András, Bedekovics, Judit, Miltényi, Zsófia, Ujfalusi, Anikó, Méhes, Gábor, Mokánszki, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654600/
https://www.ncbi.nlm.nih.gov/pubmed/36359870
http://dx.doi.org/10.3390/cells11213475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654600/
https://www.ncbi.nlm.nih.gov/pubmed/36359870
http://dx.doi.org/10.3390/cells11213475

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