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HSD3B1 Expression Is Upregulated by Interleukin 4 in HT-29 Colon Cancer Cells via Multiple Signaling Pathways

3β-Hydroxysteroid dehydrogenase/isomerase is essential for the synthesis of active steroid hormones. Interleukin 4 (IL4) induces the expression of HSD3B1 in various human cancer cell lines. Here, we demonstrated that administration of IL4 to an HT-29 colon cancer cell line induced high expression of...

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Detalles Bibliográficos
Autores principales: Chen, Hsin-Mei, Hung, Pei-Yu, Chen, Chih-Hung, Yu, Yu-Jhen, Syu, Ming-Shan, Hu, Meng-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654614/
https://www.ncbi.nlm.nih.gov/pubmed/36362361
http://dx.doi.org/10.3390/ijms232113572