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Increased Weight Gain and Insulin Resistance in HF-Fed PLTP Deficient Mice Is Related to Altered Inflammatory Response and Plasma Transport of Gut-Derived LPS

Bacterial lipopolysaccharides (LPS, endotoxins) are found in high amounts in the gut lumen. LPS can cross the gut barrier and pass into the blood (endotoxemia), leading to low-grade inflammation, a common scheme in metabolic diseases. Phospholipid transfer protein (PLTP) can transfer circulating LPS...

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Detalles Bibliográficos
Autores principales: Lebrun, Lorène J., Pallot, Gaëtan, Nguyen, Maxime, Tavernier, Annabelle, Dusuel, Alois, Pilot, Thomas, Deckert, Valérie, Dugail, Isabelle, Le Guern, Naig, Pais De Barros, Jean-Paul, Benkhaled, Anissa, Choubley, Hélène, Lagrost, Laurent, Masson, David, Gautier, Thomas, Grober, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654699/
https://www.ncbi.nlm.nih.gov/pubmed/36362012
http://dx.doi.org/10.3390/ijms232113226