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Increased Weight Gain and Insulin Resistance in HF-Fed PLTP Deficient Mice Is Related to Altered Inflammatory Response and Plasma Transport of Gut-Derived LPS
Bacterial lipopolysaccharides (LPS, endotoxins) are found in high amounts in the gut lumen. LPS can cross the gut barrier and pass into the blood (endotoxemia), leading to low-grade inflammation, a common scheme in metabolic diseases. Phospholipid transfer protein (PLTP) can transfer circulating LPS...
Autores principales: | Lebrun, Lorène J., Pallot, Gaëtan, Nguyen, Maxime, Tavernier, Annabelle, Dusuel, Alois, Pilot, Thomas, Deckert, Valérie, Dugail, Isabelle, Le Guern, Naig, Pais De Barros, Jean-Paul, Benkhaled, Anissa, Choubley, Hélène, Lagrost, Laurent, Masson, David, Gautier, Thomas, Grober, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654699/ https://www.ncbi.nlm.nih.gov/pubmed/36362012 http://dx.doi.org/10.3390/ijms232113226 |
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