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Interplay between the DNA Damage Response and Immunotherapy Response in Cancer

Genome instability and immune evasion are both defining hallmarks of cancer. Tumorigenesis is frequently initiated when there is DNA damage to a proto-oncogene or tumor suppressor gene and DNA repair mechanisms are lost or insufficient to correct the damage; immune evasion then prevents the host imm...

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Detalles Bibliográficos
Autores principales: Lee, Elizabeth Chun Yong, Kok, Jessica Sook Ting, Teh, Bin Tean, Lim, Kah Suan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654744/
https://www.ncbi.nlm.nih.gov/pubmed/36362142
http://dx.doi.org/10.3390/ijms232113356