The Organogermanium Compound 3-(Trihydroxygermyl) Propanoic Acid (THGP) Suppresses Inflammasome Activation Via Complexation with ATP

Inflammasome activity is a key indicator of inflammation. The inflammasome is activated by pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which activate the p38-NF-κB pathway and promote IL-1β transcription (signaling step 1). Next, extracellular ade...

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Detalles Bibliográficos
Autores principales: Azumi, Junya, Shimada, Yasuhiro, Takeda, Tomoya, Aso, Hisashi, Nakamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654755/
https://www.ncbi.nlm.nih.gov/pubmed/36362152
http://dx.doi.org/10.3390/ijms232113364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654755/
https://www.ncbi.nlm.nih.gov/pubmed/36362152
http://dx.doi.org/10.3390/ijms232113364

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