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Design, Synthesis, and Bioassay of 2′-Modified Kanamycin A

Chemical modification of old drugs is an important way to obtain new ones, and it has been widely used in developing new aminoglycoside antibiotics. However, many of the previous modifying strategies seem arbitrary for their lack of support from structural biological detail. In this paper, based on...

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Detalles Bibliográficos
Autores principales: Yan, Ribai, Li, Xiaonan, Liu, Yuheng, Ye, Xinshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654810/
https://www.ncbi.nlm.nih.gov/pubmed/36364310
http://dx.doi.org/10.3390/molecules27217482