Alternation of Organ-Specific Exposure in LPS-Induced Pneumonia Mice after the Inhalation of Tetrandrine Is Governed by Metabolizing Enzyme Suppression and Lysosomal Trapping

The objective of the present study was to define whether inhaled tetrandrine (TET) could be a promising way to achieve the local effect on its therapeutic efficacy based on biodistribution features using the LPS-treated acute lung injury (ALI) model. The tissue distribution profiles of inhaled TET i...

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Detalles Bibliográficos
Autores principales: Wang, Furun, Jiang, Xue, Yang, Zengxu, Fu, Shuang, Yao, Shi, Wang, Lingchao, Lv, Yue, Zhang, Wenpeng, Ding, Rigao, Zhuang, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655037/
https://www.ncbi.nlm.nih.gov/pubmed/36361734
http://dx.doi.org/10.3390/ijms232112948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655037/
https://www.ncbi.nlm.nih.gov/pubmed/36361734
http://dx.doi.org/10.3390/ijms232112948

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