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Alternation of Organ-Specific Exposure in LPS-Induced Pneumonia Mice after the Inhalation of Tetrandrine Is Governed by Metabolizing Enzyme Suppression and Lysosomal Trapping
The objective of the present study was to define whether inhaled tetrandrine (TET) could be a promising way to achieve the local effect on its therapeutic efficacy based on biodistribution features using the LPS-treated acute lung injury (ALI) model. The tissue distribution profiles of inhaled TET i...
Autores principales: | Wang, Furun, Jiang, Xue, Yang, Zengxu, Fu, Shuang, Yao, Shi, Wang, Lingchao, Lv, Yue, Zhang, Wenpeng, Ding, Rigao, Zhuang, Xiaomei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655037/ https://www.ncbi.nlm.nih.gov/pubmed/36361734 http://dx.doi.org/10.3390/ijms232112948 |
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