The Increased Amyloidogenicity of Spike RBD and pH-Dependent Binding to ACE2 May Contribute to the Transmissibility and Pathogenic Properties of SARS-CoV-2 Omicron as Suggested by In Silico Study

SARS-CoV-2 is a rapidly evolving pathogen that has caused a global pandemic characterized by several consecutive waves. Based on epidemiological and NGS data, many different variants of SARS-CoV-2 were described and characterized since the original variant emerged in Wuhan in 2019. Notably, SARS-CoV...

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Detalles Bibliográficos
Autores principales: Aksenova, Anna Y., Likhachev, Ilya V., Grishin, Sergei Y., Galzitskaya, Oxana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655063/
https://www.ncbi.nlm.nih.gov/pubmed/36362302
http://dx.doi.org/10.3390/ijms232113502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655063/
https://www.ncbi.nlm.nih.gov/pubmed/36362302
http://dx.doi.org/10.3390/ijms232113502

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