Comparison of LC-MS(3) and LC-MRM Methods for Quantifying Amantadine and Its Application in Therapeutic Amantadine Monitoring in Human Plasma

A simple sample preprocessing method was developed for the quantitative determination of amantadine (AMT) in human plasma by liquid chromatography-tandem mass spectrometry cubed (LC-MS(3)). The LC-MS(3) system comprised a Shimadzu Exion LC-20AD HPLC pump coupled with a QTRAP 5500 mass spectrometer....

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Detalles Bibliográficos
Autores principales: Sun, Qiang, Cao, Haiwei, Liu, Yong, Li, Yanyan, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655109/
https://www.ncbi.nlm.nih.gov/pubmed/36364446
http://dx.doi.org/10.3390/molecules27217619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655109/
https://www.ncbi.nlm.nih.gov/pubmed/36364446
http://dx.doi.org/10.3390/molecules27217619

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