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Comparison of LC-MS(3) and LC-MRM Methods for Quantifying Amantadine and Its Application in Therapeutic Amantadine Monitoring in Human Plasma
A simple sample preprocessing method was developed for the quantitative determination of amantadine (AMT) in human plasma by liquid chromatography-tandem mass spectrometry cubed (LC-MS(3)). The LC-MS(3) system comprised a Shimadzu Exion LC-20AD HPLC pump coupled with a QTRAP 5500 mass spectrometer....
Autores principales: | Sun, Qiang, Cao, Haiwei, Liu, Yong, Li, Yanyan, Huang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655109/ https://www.ncbi.nlm.nih.gov/pubmed/36364446 http://dx.doi.org/10.3390/molecules27217619 |
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