Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer’s Disease: From In Silico to In Vivo

Alzheimer’s disease (AD) is a complex and widespread condition, still not fully understood and with no cure yet. Amyloid beta (Aβ) peptide is suspected to be a major cause of AD, and therefore, simultaneously blocking its formation and aggregation by inhibition of the enzymes BACE-1 (β-secretase) an...

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Detalles Bibliográficos
Autores principales: Stern, Noa, Gacs, Alexandra, Tátrai, Enikő, Flachner, Beáta, Hajdú, István, Dobi, Krisztina, Bágyi, István, Dormán, György, Lőrincz, Zsolt, Cseh, Sándor, Kígyós, Attila, Tóvári, József, Goldblum, Amiram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655245/
https://www.ncbi.nlm.nih.gov/pubmed/36361906
http://dx.doi.org/10.3390/ijms232113098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655245/
https://www.ncbi.nlm.nih.gov/pubmed/36361906
http://dx.doi.org/10.3390/ijms232113098

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