Unusual Formation of 1,2,4-Oxadiazine Core in Reaction of Amidoximes with Maleic or Fumaric Esters

We have developed a simple and convenient method for the synthesis of 3-aryl- and 3-hetaryl-1,2,4-oxadiazin-5-ones bearing an easily functionalizable (methoxycarbonyl)methyl group at position 6 via the reaction of aryl or hetaryl amidoximes with maleates or fumarates. The conditions for this reactio...

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Detalles Bibliográficos
Autores principales: Presnukhina, Sofia I., Tarasenko, Marina V., Geyl, Kirill K., Baykova, Svetlana O., Baykov, Sergey V., Shetnev, Anton A., Boyarskiy, Vadim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655267/
https://www.ncbi.nlm.nih.gov/pubmed/36364335
http://dx.doi.org/10.3390/molecules27217508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655267/
https://www.ncbi.nlm.nih.gov/pubmed/36364335
http://dx.doi.org/10.3390/molecules27217508

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