Autologous iPSC-Derived Human Neuromuscular Junction to Model the Pathophysiology of Hereditary Spastic Paraplegia

Hereditary spastic paraplegia (HSP) is a heterogeneous group of genetic neurodegenerative disorders, characterized by progressive lower limb spasticity and weakness resulting from retrograde axonal degeneration of motor neurons (MNs). Here, we generated in vitro human neuromuscular junctions (NMJs)...

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Detalles Bibliográficos
Autores principales: Costamagna, Domiziana, Casters, Valérie, Beltrà, Marc, Sampaolesi, Maurilio, Van Campenhout, Anja, Ortibus, Els, Desloovere, Kaat, Duelen, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655384/
https://www.ncbi.nlm.nih.gov/pubmed/36359747
http://dx.doi.org/10.3390/cells11213351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655384/
https://www.ncbi.nlm.nih.gov/pubmed/36359747
http://dx.doi.org/10.3390/cells11213351

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