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Losartan Potassium and Verapamil Hydrochloride Compound Transdermal Drug Delivery System: Formulation and Characterization

In this study, we developed a sustained-release transdermal delivery system containing losartan potassium (LP) and verapamil hydrochloride (VPH). LP and VPH have low bioavailability and long half-life. Therefore, the development of an optimum administration mode is necessary to overcome these drawba...

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Detalles Bibliográficos
Autores principales: Chen, Yu-si, Sun, Yi-yang, Qin, Zi-chen, Zhang, Sai-ya, Chen, Wen-bo, Liu, Yan-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655391/
https://www.ncbi.nlm.nih.gov/pubmed/36361834
http://dx.doi.org/10.3390/ijms232113051