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Quantitative Proteomics Analysis Reveals That Cyclooxygenase-2 Modulates Mitochondrial Respiratory Chain Complex IV in Cardiomyocytes

The biochemical mechanisms of cell injury and myocardial cell death after myocardial infarction remain unresolved. Cyclooxygenase 2 (COX-2), a key enzyme in prostanoid synthesis, is expressed in human ischemic myocardium and dilated cardiomyopathy, but it is absent in healthy hearts. To assess the r...

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Detalles Bibliográficos
Autores principales: Alvarez, Maria Soledad, Núñez, Estefanía, Fuertes-Agudo, Marina, Cucarella, Carme, Fernandez-Velasco, Maria, Boscá, Lisardo, Vázquez, Jesús, Rossignol, Rodrigue, Martin-Sanz, Paloma, Casado, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655412/
https://www.ncbi.nlm.nih.gov/pubmed/36362254
http://dx.doi.org/10.3390/ijms232113476