Genetic Inactivation of Notch1 Synergizes with Loss of Trp53 to Induce Tumor Formation in the Adult Mouse Forebrain

SIMPLE SUMMARY: Notch signaling plays a context-dependent role in multiple cancer types by either promoting or suppressing tumor development. The role of the Notch receptors in the formation of brain tumors remains controversial. By exploiting conditional genetics and lineage tracing approaches to s...

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Detalles Bibliográficos
Autores principales: Parmigiani, Elena, Giachino, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655454/
https://www.ncbi.nlm.nih.gov/pubmed/36358826
http://dx.doi.org/10.3390/cancers14215409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655454/
https://www.ncbi.nlm.nih.gov/pubmed/36358826
http://dx.doi.org/10.3390/cancers14215409

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