Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling

Breast carcinomas are composed of cancer cells surrounded by various types of non-cancer cells such as fibroblasts. While active cancer-associated fibroblasts (CAFs) support tumor initiation and progression, quiescent breast stromal fibroblasts (BSFs) inhibit these effects through various cytokines...

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Detalles Bibliográficos
Autores principales: Al-Nasrallah, Huda K., Al-Ansari, Mysoon M., Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655455/
https://www.ncbi.nlm.nih.gov/pubmed/36359766
http://dx.doi.org/10.3390/cells11213369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655455/
https://www.ncbi.nlm.nih.gov/pubmed/36359766
http://dx.doi.org/10.3390/cells11213369

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