Hemizygous Granzyme A Mice Expressing the hSOD1G93A Transgene Show Slightly Extended Lifespan

Granzyme A (gzmA), a serine protease involved in the modulation of the inflammatory immune response, is found at an elevated level in the serum from ALS patients. However, the influence of gzmA on the progression of ALS remains unclear. The aim of our work was to assess whether the absence of gzmA i...

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Detalles Bibliográficos
Autores principales: Moreno-Martinez, Laura, Santiago, Llipsy, de la Torre, Miriam, Calvo, Ana Cristina, Pardo, Julián, Osta, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655466/
https://www.ncbi.nlm.nih.gov/pubmed/36362341
http://dx.doi.org/10.3390/ijms232113554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655466/
https://www.ncbi.nlm.nih.gov/pubmed/36362341
http://dx.doi.org/10.3390/ijms232113554

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