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Hemizygous Granzyme A Mice Expressing the hSOD1G93A Transgene Show Slightly Extended Lifespan
Granzyme A (gzmA), a serine protease involved in the modulation of the inflammatory immune response, is found at an elevated level in the serum from ALS patients. However, the influence of gzmA on the progression of ALS remains unclear. The aim of our work was to assess whether the absence of gzmA i...
Autores principales: | Moreno-Martinez, Laura, Santiago, Llipsy, de la Torre, Miriam, Calvo, Ana Cristina, Pardo, Julián, Osta, Rosario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655466/ https://www.ncbi.nlm.nih.gov/pubmed/36362341 http://dx.doi.org/10.3390/ijms232113554 |
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